ASHP Midyear 2022
Development of a Screening Tool for Opioid-Induced Endocrinopathy in Adult Patients
Research Team
University of Iowa College of Pharmacy
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Disclosures
Authors of this presentation have the following to disclose concerning possible financial or personal relationships with commercial entities that may have a direct or indirect interest in the subject matter of this presentation:
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Emma Murter, Michelle Schmidt, James Ray: Nothing to disclose
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Benjamin Miskle: Research support by grant funding from Iowa Department of Public Health (IDPH), Health Resources and Services Administration (HRSA), and Substance Abuse and Mental Health Services Administration (SAMHSA)
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Lorin Fisher: Research support by grant funding from National Institutes of Health (NIH) and National Association of Chain Drug Stores (NACDS)
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Citations
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U.S. Opioid Dispensing Rate Maps (11/10/21). Centers for Disease Control and Prevention, National Center for Injury Prevention and Control. Accessed 11/14/22. Available at: https://www.cdc.gov/drugoverdose/rxrate-maps/index.html
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U.S. Overdose Deaths In 2021 Increased Half as Much as in 2020 – But Are Still Up 15% (05/11/22). Centers for Disease Control and Prevention, National Center for Health Statistics. Accessed 11/14/22. Available at: https://www.cdc.gov/nchs/pressroom/nchs_press_releases/2022/202205.htm
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Fountas A, Chai ST, Kourkouti C, Karavitaki N. Mechanisms of endocrinology: endocrinology of opioids. Eur J Endocrinol 2018;179(4):R183-R196.
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O’Rourke TK, Wosnitzer MS. Opioid-induced androgen deficiency (OPIAD): diagnosis, management, and literature review. Curr Urol Rep 2016;17(10):76.
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Hsieh A, DiGiorgio L, Fakunle M, Sadeghi-Nejad H. Management strategies in opioid abuse and sexual dysfunction: a review of opioid-induced androgen deficiency. Sex Med Rev 2018;6(4):618-623.
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Ali K, Raphael J, Khan S, Labib M, Duarte R. The effects of opioids on the endocrine system: an overview. Postgrad Med J 2016;92(1093):677-681.
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Bawor M, Bami H, Dennis BB, et al. Testosterone suppression in opioid users: A systematic review and meta-analysis. Drug and Alcohol Depend 2015;149:1-9.
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Rajagopal A, Vassilopoulou-Sellin R, Palmer JL, Kaur G, Bruera E. Symptomatic hypogonadism in male survivors of cancer with chronic exposure to opioids. Cancer 2004;100(4):851-858.
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Aloisi AM. Opioid-induced hypogonadism: why and how to treat it. Pain Phys 2012;3S;15(3S;7):ES111-ES118.